The most common skin problems
According to the MSD Veterinary Manual, patchy hair loss is a common sign of skin trouble in guinea pigs. There are several possible causes, which only your vet can tell apart:
- Mange (mites)
- Itching that can be very intense, hair loss and inflammation, often on the inner thighs, shoulders and neck. Severe mange can cause weight loss and, according to the MSD manual, seizures or even death.
- Lice
- Itching, hair loss and irritated skin around the neck and ears; lice can be seen on the hairs with a magnifying glass.
- Ringworm (a fungus)
- Dry, scaly bald patches, often on the face, around the eyes and on the ears. Common in young guinea pigs.
- Ear mites
- The guinea pig scratches or rubs its ears, or shakes its head, according to the RSPCA.
- Fur chewing
- A bored guinea pig or a dominant companion may pull out fur: hair loss isn’t always caused by a parasite.
Ringworm: take care for the whole family
Ringworm is caused by a fungus that can spread to people and other animals, according to the MSD manual. Your vet confirms it by examining the hairs, then prescribes suitable treatment.
- Wear disposable gloves to handle an affected guinea pig, and wash your hands afterwards.
- Disinfect their enclosure throughout the treatment, as your vet directs.
Why you shouldn’t treat them yourself
Mange, lice and ringworm look alike, and other conditions cause the same signs. Your vet will take a skin scraping or examine the hairs, then choose the treatment, applied to the skin or given by injection.
Several guinea pigs: treating the group
- Mites spread through contact with an affected companion or through bedding, according to the MSD manual: your vet decides whether the whole group needs treating.
- The PDSA recommends taking your guinea pigs to the vet together, even if only one shows signs, unless advised otherwise.
- A newcomer should be checked before joining the group; if they have a skin problem, keep them separate but within sight of the others until treatment is finished, according to the PDSA.
Prevention
- A clean enclosure: spot-clean every day, a full clean every week, and hay and bedding free of dust and mould.
- As little stress as possible: a stressed or ill guinea pig is more vulnerable to parasites, according to the Royal Veterinary College.
- A daily look at their coat, and regular grooming, more often for long-haired guinea pigs.
- In warm weather, check their bottom twice a day: flies can lay eggs there (flystrike), an emergency that is often fatal according to the RSPCA.
When to see a vet
Treatment and follow-up in the health record
Note your vet’s diagnosis, the treatment and its dates in MyArk: everyone in the household knows where things stand, and the history is there if the signs come back.
- Past and current treatments, for each guinea pig
- Upcoming dates, sent to everyone in the household
- A dated note when you spot a bald patch or itching
- The weight chart, to see if they’re losing weight
Common questions
Do guinea pigs need worming?
Not routinely: according to the Royal Veterinary College, guinea pigs don’t need yearly worming. Your vet treats if they find parasites, as the RSPCA points out.
My guinea pig is scratching a lot: is it mange?
It might be, but lice, ringworm or a behaviour problem cause similar signs. Only your vet can tell the difference, by examining the skin.
Can people catch ringworm from guinea pigs?
Yes, according to the MSD Veterinary Manual: it spreads to people and other animals. Wear disposable gloves to handle your guinea pig during treatment and wash your hands afterwards.
Can I use my dog’s or cat’s flea treatment?
No. Medicines meant for other animals are dangerous for guinea pigs. Always ask your vet.
Do all the guinea pigs in the hutch need treating?
Mites spread through contact and through bedding: take the group to the vet, as the PDSA advises, and your vet will decide who needs treating.
What is flystrike?
Flies lay eggs on a dirty bottom, and the maggots attack the skin. It is extremely painful and often fatal: in summer, check their bottom twice a day and call your vet as soon as you see maggots.
Sources
Benchmarks checked on 21 October 2026 in the documents below, then rewritten in plain English. They do not replace an examination and advice from your vet, who adapts care to your pet and to where you live.
- MSD Veterinary Manual, Skin Problems of Guinea Pigs (2025)
- RSPCA, Guinea pig health and welfare
- RSPCA, How to take care of your guinea pigs — booklet (2023)
- PDSA, Five common health problems in guinea pigs and how to prevent them (2024)
- PDSA, Guinea pig health
- Royal Veterinary College, Beaumont Sainsbury Animal Hospital (exotics service), Caring for your guinea pig
- Blue Cross, How to keep guinea pigs cool in the summer
